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If the effects of OC (oleoresin capsicum) exposure last for 30 minutes or more, seeking medical attention is essential. Prolonged exposure to OC can result in severe physical reactions such as difficulty breathing, prolonged irritation of the eyes and skin, or even more severe systemic effects. Medical professionals can assess the situation accurately and provide appropriate treatment, which may include decontamination and supportive care.

While natural recovery is often acceptable if symptoms are mild and manageable, a duration of over 30 minutes suggests that the individual may require more than just basic first aid. Waiting for the natural recovery process in such cases could lead to worsening symptoms or complications. Reapplying water or lotion might provide temporary relief but would not address underlying issues effectively if symptoms persist for an extended time. Hence, ensuring the individual receives professional medical evaluation is the safest course of action.